First, CuteNews seems to be some sort of CMS that uses a flatfile database, so you won't be able to use it with Zencart.

You will be able to make your Zencart site look like your image, but you have a lot of stuff to learn about Zencart and CSS first.

1. Read through the Tutorials/FAQ section

2. Browse through the Admin area to see what is done there (including turning sideboxes on and off).

3. Install the Firefox browser and the Web Developer plugin for Firefox. You can use those to see where in the stylesheet you change the styling of the various page elements.

Ctrl-Shift-Y will allow you to hover over a section of the page and see the class and id names for that section in the box at the top. The statements in the stylesheet that begin with # are id's and the ones that begin with dots are classes.

Ctrl-Shift-E will open the CSS editor and allow you to edit the stylesheet and see the changes in real time without changing anything permanently. An essential tool.

Some prefer Firebug, which does much the same thing.