I have marked in RED some oddities I noticed.

// define our database connection
define('DB_TYPE', 'mysql');
define('DB_PREFIX', 'zen'); // prefix for database table names -- preferred to be left empty
define('DB_SERVER', 'bylargesse.com');
define('DB_SERVER_USERNAME',######_zc1'root');
define('DB_SERVER_PASSWORD', '##########'');
define('DB_DATABASE', '######_zc1'');
define('USE_PCONNECT', 'false');
define('STORE_SESSIONS', 'db');
// use 'db' for best support, or '' for file-based storage
// The next 2 "defines" are for SQL cache support.
// For SQL_CACHE_METHOD, you can select from: none, database, or file
// If you choose "file", then you need to set the DIR_FS_SQL_CACHE to a directory
where your apache
// or webserver user has write privileges (chmod 666 or 777). We recommend using the "cache" folder inside the Zen Cart folder
// ie: /path/to/your/webspace/public_html/zen/cache -- leave no trailing slash
define('SQL_CACHE_METHOD', 'none');
define('DIR_FS_SQL_CACHE',
'/home/#######/public_html/cache');


Compare to what I think they should be.

// define our database connection
define('DB_TYPE', 'mysql');
define('DB_PREFIX', 'zen_'); // prefix for database table names -- preferred to be left empty
define('DB_SERVER', 'localhost');
define('DB_SERVER_USERNAME', '######_zc1root');
define('DB_SERVER_PASSWORD', '##########');
define('DB_DATABASE', '######_zc1');
define('USE_PCONNECT', 'false');
define('STORE_SESSIONS', 'db');
// use 'db' for best support, or '' for file-based storage
// The next 2 "defines" are for SQL cache support.
// For SQL_CACHE_METHOD, you can select from: none, database, or file
// If you choose "file", then you need to set the DIR_FS_SQL_CACHE to a directory
where your apache
// or webserver user has write privileges (chmod 666 or 777). We recommend using the "cache" folder inside the Zen Cart folder
// ie: /path/to/your/webspace/public_html/zen/cache -- leave no trailing slash
define('SQL_CACHE_METHOD', 'none');
define('DIR_FS_SQL_CACHE', '/home/#######/public_html/cache');


Although I do not know what type of Server your account is on nor how it is setup for database usage, the above oddities are worth checking out to see if changes are required. Check with your Hoster if not sure.