On the standard template of Zencart, Can I not having the right column but organize its function into the left column?
In the admin > config > layout settings > Column Right Status - Global > set to "0"
and then in the admin > tools > layout box controller you can enable & diable and move from right to left and sideboxes that you might want.

I do not have any experience with travel service but have seen other Zen Carts that are for that purpose