Okay...
Header: It is a standard process to put your custom logo in the header, and there are several ways you could get the navigation links as shown. You might want to add a bar or something to hold more links, as there are many more than the four pages you show that will be needed for a complete website (they are already part of Zen Cart).
Main content area: You can turn off both sidebars for some pages, and have just the right sidebar for pages where you want the product special ad. You can use a banner sidebox to hold that ad and others if you want to rotate them.
Homepage "Franko Prodcom SRL..." content (currently just one image) can go in define_main_page.php (edit in admin).
That content is easily readable by humans, but search engines cannot read the image and will not be able to find your page when people are searching for that information. Consider adding text, plain or alt, so there is searchable content on the homepage. Zen Cart has built-in metatag handling so you can easily give a good description for SE's to use.
Footer: You can use a bannerbox in the footer to hold the three ads there, and you may want to use the ez-pages footer menu to give a full set of navigation links at the bottom of the page.
All in all, nothing looks like a big deal to translate to Zen Cart.